Dr Michael Coogan

Senior Lecturer

Profile

Mike Coogan was born in Birkenhead (UK) in 1969 and attended University of Leicester for both his BSc and PhD (with Dr R. S. Atkinson, studying asymmetric alkene aziridination). After postdocs in Nottingham, Cardiff and Sheffield he took up a temporary lectureship in Organic Chemistry at Durham in 1998. In 2000, he moved to Cardiff, initially as an organic chemist, before joining the Inorganic Chemistry research grouping, of which he became group leader in 2009. Current research interests include organometallic and coordination chemistry and the biological applications of coordination complexes.

Platinum trimethyl bipyridyl thiolates – new, tunable, red- to near IR emitting luminophores for bioimaging applications
Steel, H., Allinson, S., Andre, J., Coogan, M., Platts, J.A. 1/07/2015 In: Chemical Communications. 51, 57, p. 11441-11444. 4 p.
Journal article

Single amino acid chelate complexes of the M (CO)(3)(+) core for correlating fluorescence and radioimaging studies (M=Tc-99m or Re)
Coogan, M., Doyle, R.P., Valliant, J.F., Babich, J.W., Zubieta, J. 04/2014 In: Journal of Labelled Compounds and Radiopharmaceuticals. 57, 4, p. 255-261. 7 p.
Journal article

Experimental and theoretical characterisation of phosphorescence from rhenium polypyridyl tricarbonyl complexes
Thorp-Greenwood, F.L., Platts, J.A., Coogan, M. 8/01/2014 In: Polyhedron. 67, p. 505-512. 8 p.
Journal article

Progress with, and prospects for, metal complexes in cell imaging
Coogan, M., Fernandez-Moreira, V. 2014 In: Chemical Communications. 50, p. 384-399. 16 p.
Journal article

Emission wavelength variation with changes in excitation in a Re(I)–bisthiazolate ligand complex that breaks the Kasha–Vavilov rule
Henry, K.E., Balasingham, R.G., Vortherms, A.R., Platts, J.A., Valliant, J.F., Coogan, M., Zubieta, J., Doyle, R.P. 1/06/2013 In: Chemical Science. 4, 6, p. 2490-2495. 6 p.
Journal article

Simple polyphenyl zirconium and hafnium metallocene room-temperature lumophores for cell imaging
Pritchard, V.E., Thorp-Greenwood, F.L., Balasingham, R.G., Williams, C.F., Kariuki, B.M., Platts, J.A., Hallett, A.J., Coogan, M. 2013 In: Organometallics. 32, 12, p. 3566–3569. 4 p.
Journal article

Organometallic complexes of transition metals in luminescent cell imaging applications
Thorp-Greenwood, F.L., Balasingham, R.G., Coogan, M. 1/09/2012 In: Journal of Organometallic Chemistry. 714, p. 12-21. 10 p.
Journal article

Introduction to the Organometallics in Biology and Medicine Issue
Coogan, M., Dyson, P.J., Bochmann, M. 27/08/2012 In: Organometallics. 31, 16, 2 p.
Editorial

Gold (I) Complexes Derived From Alkynoxy-substituted Anthraquinones: Syntheses, Luminescence, Cytotoxicity and Cell Imaging Studies,
Balasingham, R.G., Williams, C.F., Mottram, H.J., Coogan, M., Pope, S.J.A. 16/08/2012 In: Organometallics. 31, 16, p. 5835-5843. 9 p.
Journal article

Bioconjugated Rhenium(I) Complexes with Amino Acid Derivatives: Synthesis, Photophysical Properties, and Cell Imaging Studies
Coogan, M. 2012 In: Organometallics. 31
Journal article

Biologically compatible, phosphorescent dimetallic rhenium complexes linked through functionalized alkyl chains: syntheses, spectroscopic properties, and applications in imaging microscopy
Balasingham, R.G., Thorp-Greenwood, F.L., Williams, C.F., Coogan, M., Pope, S.J.A. 2012 In: Inorganic Chemistry. 51, 3, p. 1419–1426. 8 p.
Journal article

Parasites pitched against nature: Pitch Lake water protects guppies (Poecilia reticulata) from microbial and gyrodactylid infections
Schelkle, B., Mohammed, R.S., Coogan, M., McMullen, M., Gillingham, E.L., Van Oosterhout, C., Cable, J. 2012 In: Parasitology. 139, 13, p. 1772-1779. 8 p.
Journal article

The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors.
Thorp-Greenwood, F.L., Coogan, M., Mishra, L., Kumari, N., Rai, G., Saripella, S. 2012 In: New Journal of Chemistry. 36, 1, p. 64-72. 9 p.
Journal article

A ‘Sleeping Trojan Horse’ which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging
Thorp-Greenwood, F.L., Fernandez-Moreira, V., Millet, C., Williams, C.F., Cable, J., Court, J.B., Hayes, A.J., Lloyd, D., Coogan, M. 2011 In: Chemical Communications. 47, 11, p. 3096-3098. 3 p.
Journal article

Carbohydrate and amino acid metabolism of the diplomonad parasite Spironucleus vortens
Millet, C., Lloyd, D., Coogan, M., Rumsey, J., Cable, J. 2011 In: Experimental Parasitology. 129, 1, p. 17-26. 10 p.
Journal article

Complexes in context: attempting to control the cellular uptake and localisation of rhenium fac-tricarbonyl polypyridyl complexes
Balasingham, R.G., Coogan, M., Thorp-Greenwood, F.L. 2011 In: Dalton Transactions. 40, 44, p. 11663-11674. 12 p.
Journal article

Cytotoxic activity, cell imaging and photocleavage of DNA induced by a Pt(II) cyclophane bearing 1,2 diamino ethane as a terminal ligand
Coogan, M. 2011 In: MedChemComm. 2, 12, p. 1208-1216. 9 p.
Journal article

Multimodal Radio- (PET / SPECT) and Fluorescence Imaging Agents Based on Metallo-Radioisotopes: Current Applications and Prospects for Development of New Agents
Thorp-Greenwood, F.L., Coogan, M. 2011 In: Dalton Transactions. 40, 23, p. 6129-6143. 15 p.
Journal article

Application of d6 transition metal complexes in fluorescence cell imaging
Fernandez-Moreira, V., Thorp-Greenwood, F.L., Coogan, M. 2010 In: Chemical Communications. 46, 2, p. 186-202. 17 p.
Journal article

Fluxionality and Lability in Rhenium 4’-Hydroxyterpyridine complexes: Evidence for an Associative Mechanism and Cooperative Fluxionality and Lability
Fernandez-Moreira, V., Thorp-Greenwood, F.L., Arthur, R.J., Kariuki, B., Jenkins, R.L., Coogan, M. 2010 In: Dalton Transactions. 39, 32, p. 7493-7503. 11 p.
Journal article

Functionalisation of terpyridine complexes containing the [Re(CO)3Cl]+ moiety
Amoroso, A.J., Banu, A., Coogan, M., Edwards, P.G., Hossain, G., Abdul Malik, K.M. 2010 In: Dalton Transactions. 39, 30, p. 6993-7003. 11 p.
Journal article

Probing intracellular oxygen by quenched phosphorescence lifetimes of nanoparticles containing polyacrylamide-embedded [Ru(dpp(SO3Na)2)3]Cl2
Coogan, M., Court, J.B., Gray, V.L., Hayes, A.J., Lloyd , S.H., Millet, C., Pope, S.J.A., Lloyd, D. 2010 In: Photochemical and Photobiological Sciences. 9, 1, p. 103-109. 7 p.
Journal article

Uptake and Localisation of Rhenium fac-Tricarbonyl Polypyridyls in Fluorescent Cell Imaging Experiments, Establishing The Ground-Rules For Fluorescent Cell Imaging With Rhenium fac-Tricarbonyl Polypyridyl Complexes
Fernández-Moreira, V., Thorp-Greenwood, F.L., Amoroso, A.J., Cable, J., Court, J.B., Gray, V.L., Hayes, A.J., Jenkins, R.L., Kariuki, B.M., Lloyd, D., Millet, C., Williams, C.F., Coogan, M. 2010 In: Organic and Biomolecular Chemistry . 8, 17, p. 3888-3901 . 14 p.
Journal article

A rhenium tricarbonyl 4’-oxo-terpy trimer as a luminescent molecular vessel with a removable silver stopper
Coogan, M., Fernandez-Moreira, V., Kariuki, B., Pope, S.J.A., Thorp-Greenwood, F.L. 2009 In: Angewandte Chemie International Edition. 48, 27, p. 4965-4968. 4 p.
Journal article

Design and synthesis of substituted imidazole and triazole N-phenylbenzo[d]oxazolamine inhibitors of retinoic acid metabolizing enzyme CYP26
Pautus, S., Aboraia, A.S., Bassett, C.E., Brancale, A., Coogan, M., Simons, C. 2009 In: Journal of Enzyme Inhibition and Medicinal Chemistry. 24, 2, p. 487-498. 12 p.
Journal article

Rhenium fac-tricarbonyl bisimine complexes: luminescence modulation by hydrophobically driven intramolecular interactions
Coogan, M., Fernandez-Moreira, V., Hess, J.B., Pope, S.J.A., Williams, C. 2009 In: New Journal of Chemistry. 33, 5, p. 1094-1099. 6 p.
Journal article

Stereostructural behaviour of N–N atropisomers: two conglomerate crystallisations and a crystallisation-induced deracemisation
Arthur, R.J., Coogan, M., Casadesus, M., Haigh, R., Headspith, D.A., Grazia Francesconi , M., Laye, R.H. 2009 In: CrystEngComm. 11, 4, p. 610-619. 19 p.
Journal article

Syntheses, structural studies and spectroscopic characterisation of pyridyl–phthalimide complexes of fac-(CO)3ReI-diimines
Thorp-Greenwood, F.L., Coogan, M., Hallett, A.J., Laye, R.H., Pope, S.J.A. 2009 In: Journal of Organometallic Chemistry. 694, 9-10, p. 1400-1406. 7 p.
Journal article

The coordination chemistry of fluorescent pyridinyl- and quinolinyl-phthalimide ligands with the {Au-I-PPh3} cationic unit
Mullice, L.A., Thorp-Greenwood, F.L., Laye, R.H., Coogan, M., Kariuki, B., Pope, S.J.A. 2009 In: Dalton Transactions. 38, 34, p. 6836-6842. 6 p.
Journal article

3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria
Amoroso, A.J., Arthur, R.J., Coogan, M., Court, J.B., Fernandez-Moreira, V., Hayes, A.J., Lloyd, D., Millet, C., Pope, S.J.A. 2008 In: New Journal of Chemistry. 32, 7, p. 1097-1102. 16 p.
Journal article

Dicobaltbisnorbornadienetetracarbonyl [Co2(nbd)2(CO)4] reacts with oxygen-containing alkynes and gives crossover products in the presence of other alkenes
Coogan, M., Wilkins, D.S. 2008 In: Journal of Chemical Research. 2008, 9, p. 516-519. 4 p.
Journal article

Stereochemical studies of cobalt ethylenediamine complexes and their tetrathionate salts: interactions between complex configuration and tetrathionate conformation
Casadesus, M., Coogan, M., Davies, E., Ooi, L. 2008 In: Inorganica Chimica Acta. 361, 1, p. 63-78. 16 p.
Journal article